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Clinical Approach to Parkinson's Disease: Features, Diagnosis, and Principles of Management

Year: 2012

Type: preprint

Abstract: Parkinson's disease (PD) is one of the most common neurodegenerative disorders. The condition causes a heavy burden both on those affected, as well as their families. Accurate diagnosis is critical and remains founded on clinical grounds as no specific diagnostic test is available so far. The clinical picture of PD is typical in many instances; however, features distinguishing it from other disorders should be thoroughly sought. Monogenic forms of PD also have some distinctive characteristics in many cases. This text is a roadmap to accurate diagnosis in PD, as it approaches clinical features, diagnostic methodology, and leading differential diagnoses. Therapeutic issues are also briefly discussed.

Source: Cold Spring Harbor Perspectives in Medicine

DOI: 10.1101/cshperspect.a008870

Authors: J. Massano, K. P. Bhatia

Institutions: Universidade do Porto, Hospital de São João, National Hospital for Neurology and Neurosurgery, UCL Queen Square Institute of Neurology, University College London

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2133398254

Cites: 139

Cited by: 451

Related to: 10