In-vivo pilot study on physical absorption enhancement of active skin whitening ingredients by heat and ultrasound
Year: 2012
Type: report
Abstract: In Q3 of 2011, Philips Research received a brief from the Skin Carecategory of the Philips Consumer Lifestyle sector to explore the feasibility of heat and ultrasound to increase skin uptake of active skin whitening ingredients from cosmetics. Philips Research Asia-Shanghai performed an in-vivo study which aimed to answer two questions:1. Shows heat or ultrasound any efficacy in this context? 2. If an enhancement can be achieved, which technology is more suitable for ahome-use device? This report summarizes the research activities which have been conducted in Shanghai over Q3-Q4 of 2011 to answer thesequestions. Furthermore, mechanisms behind heat- and ultrasound-mediated permeation enhancement are introduced and discussed including mathematical models which can be used to predict permeation behaviourbased on physiochemical properties of a penetrant.
Authors: M.M. Scheja, X. Wang, Ping Ma
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2133483045