Year: 1999
Type: editorial
Abstract: There is no doubt that candidate gene association studies can play a useful part in detecting genetic variations contributing to complex diseases such as Alzheimer’s disease.1 Yasuda et al present a paper in this issue (pp772-6) in which they use this approach to test for an association between the 1-1 genotype of an intronic polymorphism in the presenilin 1 (PS-1) gene and Alzheimer’s disease, originally reported by Wragg et al .2 Although Yasuda et al did not replicate this effect …
Authors: J. WILLIAMS, P. G KEHOE, M. J OWEN
Institution: University of Wales
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2133600154