Work

Prostate Cancer SubtyPINg BiomarKers and Outcome: Is Clarity EmERGing?

Year: 2014

Type: article

Abstract: Molecular prostate cancer subtypes have been proposed on the basis of mutually exclusive SPINK1 and ERG overexpression, with conflicting reports on their prognostic ability. Flavin and colleagues report that SPINK1 is neither prognostic nor absolutely mutually exclusive with ERG, raising important questions about prostate cancer molecular subtyping and prognostic biomarker evaluation.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-14-0818

Authors: Steven C. Smith, Scott A. Tomlins

Institutions: Cedars-Sinai Medical Center, University of Michigan, Michigan Medicine, Michigan Center for Translational Pathology, U-M Rogel Cancer Center

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute