Risk Factors of Symptomatic and Asymptomatic Osteoarthritis of the Knee
Year: 2005
Type: article
Study design: Observational Study
Abstract: Objective To determine the risk factors of osteoarthritis (OA) of the knee. Design Unmatched case-control study. Setting Dr.Soetomo Hospital Surabaya, a tertiary government hospital. Methods 239 cases of symptomatic - radiographic (Kellgren-Lawrence I or more) OA of the knee taken from rheumatology out-patient clinic, and 175 cases of asymptomatic - radiographic (Kellgren-Lawrence I or more) OA of the knee and 279 controls without radiographic (Kellgren-Lawrence 0) OA of the knee taken from General Internal Medicine Out-patient Clinic at the same hospital were analyzed through multiple logistic regressions. Group compared A. Symptomatic cases compared to controls. B. Asymptomatic cases compared to controls. C. Their women subsets compared to that of controls. Results 1) Symptomatic cases compared to controls age > 50 (aOR 1.86, 95% CI 1.78-2.82), being female (aOR 2.08,95% CI 1.35-3.50), BMI > 25 units (aOR 3.28,95% CI 2.20-4.89), elementary education (aOR 0.29, 95% CI 0.14-0.61), genu valgus (aOR 4.07, 95% CI 2.43-7.93). 2) Women subset of symptomatic cases compared to that of controls age > 50 (aOR 9.34,95% CI 4.77-18.24), BMI > 25 units (aOR 5.27,95% CI 2.85-9.73), genu valgus (aOR 13.64, 95% CI 4.58-41.44). 3) Asymptomatic cases compared to controls age > 50 (aOR 2.31,95% CI 1.53-3.50),BMI > 25 units (aOR 1.57,95% CI 1.02-2.45). 4) Women subset of asymptomatic cases compared to that of controls age > 50 (aOR 2.07, 95% CI 1.14-2.77). Conclusions 1.Age > 50, being female, BMI > 25 units, genu valgus, are the risk factors for symptomatic OA of the knee 2. Age > 50 and BMI > 25 units are the risk factors for asymptomatic OA of the knee. 3. Being female, BMI > 25 units, genu valgus may be the factors that associated with the development symptoms of OA of the knee.
Source: Folia Medica Indonesiana
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $98
OpenAlex ID: W2134118539