Work

Image reconstruction in photoacoustic tomography involving layered acoustic media

Year: 2011

Type: article

Abstract: Photoacoustic tomography (PAT), also known as thermoacoustic or optoacoustic tomography, is a rapidly emerging biomedical imaging technique that combines optical image contrast with ultrasound detection principles. Most existing reconstruction algorithms for PAT assume the object of interest possesses homogeneous acoustic properties. The images produced by such algorithms can contain significant distortions and artifacts when the object's acoustic properties are spatially variant. In this work, we establish an image reconstruction formula for PAT applications in which a planar detection surface is employed and the to-be-imaged optical absorber is embedded in a known planar layered acoustic medium. The reconstruction formula is exact in a mathematical sense and accounts for multiple acoustic reflections between the layers of the medium. Computer-simulation studies are conducted to demonstrate and investigate the proposed method.

Source: Journal of the Optical Society of America A

DOI: 10.1364/josaa.28.001114

Authors: Robert W. Schoonover, Mark A. Anastasio

Institutions: Illinois Institute of Technology, Washington University in St. Louis

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering