In vitro inhibitory activity of Bifidobacterium and Lactobacillus strains against Candida albicans.
Year: 2013
Type: article
Abstract: Summary Denkova, R. V. Yanakieva, Z. Denkova, V. Nikolova & V. Radeva, 2013. In vitro inhibi7 tory activity of Bifidobacterium and Lactobacillus strains against Candida albicans. Bulg. J. Vet. Med. , 16, No 3, 186 −197. One of the requirements to probiotic cultures is to exhibit high antimicrobial activity against pathogenic microorganisms. The aim of this work was to determine the degree of suppression of Candida albicans by strains lactobacilli and bifidobacteria of human origin. Тhe antifungal activity of four strains of lactobacilli and bifidobacteria of human origin - Lactobacillus acidophilus A2, Lactobacillus acidophilus Ac, Lactobacillus delbrueckii ssp. bulgaricus GB and Bifidobacterium bifidum sp. 4 - against Candida albicans NBIMCC 74 by co7cultivation under static conditions at 37°C in skimmed milk was studied. Despite the high concentration of viable cells of lactobacilli or bifidobacteria, all four strains restrained the growth of the pathogen (biostatic action) and by the 72 nd hour of co7cultivation the pathogen retained high concentration of viable cells. The measured high titratable acidity during the co7cultivation of lactobacilli or bifidobacteria and the pathogen did not affect the growth of the pathogen. The performed studies are of potential importance in the treatment of candidiasis in humans and animals. The tested strains are a primary basis for the creation of probiotics for the treatment of these serious diseases.
Language: English
Subfield: Food Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2134403513