Functional Mesoporous Silica Nanoparticles for Photothermal‐Controlled Drug Delivery In Vivo
Year: 2012
Type: article
Abstract: Release me! A new class of photothermal-responsive [2]rotaxane-appended mesoporous silica nanoparticles (MSNPs) was developed. Remote-controlled movement of the α-cyclodextrin ring (green) upon trans–cis isomerization of the azobenzene axle (red) enables the loading and release of drugs on demand (see scheme). Curcumin-loaded MSNPs were shown to release curcumin into zebrafish larvae upon treatment with visible light or heat.
Authors: Hong Yan, Cathleen Teh, Sivaramapanicker Sreejith, Liangliang Zhu, Anna Kwok, Weiqin Fang, Xing Ma, Kim Truc Nguyen, Vladimir Korzh, Yanli Zhao
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: bronze
Awards: G6562987627, G8417617667
OpenAlex ID: W2134682804