Year: 2010
Type: article
Abstract: Proteomics techniques have been used to generate comprehensive lists of protein interactions in a number of species. However, relatively little is known about how these interactions result in functional multiprotein complexes. This gap can be bridged by combining data from proteomics experiments with data from established structure determination techniques. Correspondingly, integrative computational methods are being developed to provide descriptions of protein complexes at varying levels of accuracy and resolution, ranging from complex compositions to detailed atomic structures.
Source: Molecular & Cellular Proteomics
Institutions: QB3, Tel Aviv University, University of California, San Francisco
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
Awards: IMP: Software for Hybrid Determination of Macromolecular Assembly Structures, G1913224096, Protein Modeling by Satisfaction of Spatial Restraints, G565063786, Integrated modeling of biological nanomachines, New Tools for Exploring the Dynamic Interactome (Renewal), G9000201528, G9000222323, G9000283987, G9000296916, G9000316677
OpenAlex ID: W2134695030