Work

Gene regulatory networks in embryonic stem cells and brain development

Year: 2009

Type: review

Abstract: Embryonic stem cells (ESCs) are endowed with the ability to generate multiple cell lineages and carry great therapeutic potentials in regenerative medicine. Future application of ESCs in human health and diseases will embark on the delineation of molecular mechanisms that define the biology of ESCs. Here, we discuss how the finite ESC components mediate the intriguing task of brain development and exhibit biomedical potentials to cure diverse neurological disorders.

Source: Birth Defects Research Part C Embryo Today Reviews

DOI: 10.1002/bdrc.20149

Authors: Dhimankrishna Ghosh, Xiaowei Yan, Qiang Tian

Institution: Institute for Systems Biology

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green