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Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP

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Year: 2006
Type: article
Source: Bioorganic & Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2006.01.030
Authors: Mark E. Fraley, Robert M. Garbaccio, Kenneth L. Arrington, William F. Hoffman, Edward S. Tasber, Paul J. Coleman, Carolyn A. Buser, Eileen S. Walsh, Kelly Hamilton, Christine Fernandes, Michael D. Schaber, Robert B. Lobell, Weikang Tao, Victoria J. South, Youwei Yan, Lawrence C. Kuo, Thomayant Prueksaritanont, Cathy Shu, Maricel Torrent, David C. Heimbrook, Nancy E. Kohl, Hans E. Huber, George D. Hartman
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English

Topic: Microtubule and mitosis dynamics
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W2134828529
FWCI: 5.244
Cites: 15
Cited by: 64
Related to: 10
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