Work

Fatal abdominal sarcomatosis secondary to gastrointestinal stromal tumor with bland histology

Year: 2009

Type: article

Abstract: Fatal abdominal sarcomatosis is a rare complication secondary to gastrointestinal stromal tumor (GIST) arising from the small intestine. Here, we describe a 49-year-old man who presented with massive ascites and multiple mesenteric solid masses. Autopsy showed large necrotic mass (19 x 14 x 8.0 cm) surrounding the terminal ileum with multiple smaller nodules on the omentum and mesentery. Histological examination revealed highly cellular, predominantly bland, spindle cells with low mitotic activity. Gastrointestinal stromal tumor was confirmed by strong positive staining for c-KIT (CD 117). Our case is an example of fatal intra-abdominal sarcomatosis of GIST where the histological features were essentially bland.

Source: Saudi Medical Journal

DOI: 10.15537/1658-3175.4887

Authors: Yasmin M. Elshenawy, Charles E. Ganote, Mousa A. Al-Abbadi

Institutions: East Tennessee State University, James H. Quillen VA Medical Center

Language: English

Topic: Gastrointestinal Tumor Research and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2135110313

FWCI: 0.962

Cites: 11

Cited by: 3

Related to: 10