Year: 2014
Type: review
Abstract: Over the last decade, technological advances have revolutionised efforts to understand the role played by microbes in airways disease. With the application of ever more sophisticated techniques, the literature has become increasingly inaccessible to the non-specialist reader, potentially hampering the translation of these gains into improvements in patient care. In this article, we set out the key principles underpinning microbiota research in respiratory contexts and provide practical guidance on how best such studies can be designed, executed and interpreted. We examine how an understanding of the respiratory microbiota both challenges fundamental assumptions and provides novel clinical insights into lung disease, and we set out a number of important targets for ongoing research.
Source: Thorax
Institutions: Flinders University, South Australian Health and Medical Research Institute, University of Nottingham, Nottingham City Hospital, Charles Darwin University, Menzies School of Health Research, University Hospital Southampton NHS Foundation Trust, Translational Research Institute, The University of Queensland, Mater Research, Mater Adult Hospital, King's College London
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funder: University of Nottingham
OpenAlex ID: W2136243031