Work

Regulation of Expression of the Fibronectin-Binding Protein BBK32 in Borrelia burgdorferi

Year: 2007

Type: article

Abstract: The BBK32 protein binds to host extracellular ligand fibronectin and contributes to the pathogenesis of Borrelia burgdorferi. Here we showed that expression of the BBK32 gene is influenced by multiple environmental factors and that its regulation is governed by the response regulator Rrp2 and RpoN-RpoS (sigma(54)-sigma(S)) sigma cascade in B. burgdorferi.

Source: Journal of Bacteriology

DOI: 10.1128/jb.01199-07

Authors: Ming He, Bethany K. Boardman, Dalai Yan, X. Frank Yang

Institutions: Indiana University Indianapolis, Indiana University School of Medicine

Language: English

Topic: Vector-borne infectious diseases

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases