Work

Flow Cytometry and Solid Organ Transplantation: A Perfect Match

Year: 2014

Type: review

Abstract: In the field of transplantation, flow cytometry serves a well-established role in pre-transplant crossmatching and monitoring immune reconstitution following hematopoietic stem cell transplantation. The capabilities of flow cytometers have continuously expanded and this combined with more detailed knowledge of the constituents of the immune system, their function and interaction and newly developed reagents to study these parameters have led to additional utility of flow cytometry-based analyses, particularly in the post-transplant setting. This review discusses the impact of flow cytometry on managing alloantigen reactions, monitoring opportunistic infections and graft rejection and gauging immunosuppression in the context of solid organ transplantation.

Source: Immunological Investigations

DOI: 10.3109/08820139.2014.910022

Authors: Orla Maguire, Joseph D. Tario, Thomas C. Shanahan, Paul K. Wallace, Hans Minderman

Institutions: Roswell Park Comprehensive Cancer Center, University at Buffalo, State University of New York

Language: English

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute