Work

Identifying protein-coding genes in genomic sequences

Year: 2009

Type: review

Abstract: The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.

Source: Genome biology

DOI: 10.1186/gb-2009-10-1-201

Authors: Jennifer Harrow, Alinda Nagy, Alexandre Reymond, Tyler Alioto, Laszlo Patthy, Stylianos E Antonarakis, Roderic Guigó

Institutions: Wellcome Sanger Institute, Institute of Molecular Life Sciences, Hungarian Academy of Sciences, University of Lausanne, Universitat Pompeu Fabra, University of Geneva, University Hospital of Geneva

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,490

Funders: Wellcome Trust, European Commission, Nemzeti Kutatási és Technológiai Hivatal, National Institutes of Health, National Human Genome Research Institute

Awards: Vertebate genome annotation. The creation of the reference genesets for human, mouse and zebrafish., G464362581, Integrated human genome annotation: generation of a reference gene set, Mapping Sites of Transcription and Regulation, G6982995691, The Encyclopedia of Genes and Gene Variants

OpenAlex ID: W2137096454

FWCI: 0.688

Cites: 55

Cited by: 101

Related to: 10