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Distribution of Gefitinib to the Brain Is Limited by P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2)-Mediated Active Efflux

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Year: 2010
Type: article
Source: Journal of Pharmacology and Experimental Therapeutics
DOI: 10.1124/jpet.110.167601
Authors: Sagar Agarwal, Ramola Sane, Jose L. Gallardo, John R. Ohlfest, William F. Elmquist
Institution: University of Minnesota
Language: English

Topic: Drug Transport and Resistance Mechanisms
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Children's Cancer Research Fund, AstraZeneca, University of Minnesota, National Institutes of Health, National Cancer Institute
Awards: G1456749934, Improving Delivery of Molecularly-Targeted Therapy to Invasive Glioma Cells
OpenAlex ID: W2137632859
FWCI: 12.35
Cites: 41
Cited by: 258
Related to: 10
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