Work

A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence

Year: 1998

Type: preprint

Abstract: We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation.

Source: Genome Research

DOI: 10.1101/gr.8.9.967

Authors: Liliana Florea, George Hartzell, Zheng Zhang, Gerald M. Rubin, Webb Miller

Institution: Pennsylvania State University

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Human Genome Research Institute, U.S. National Library of Medicine

Awards: G232264332, SOFTWARE FOR ANALYZING BIOSEQUENCE DATA