Work

HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia

Year: 2015

Type: article

Source: Leukemia

DOI: 10.1038/leu.2015.222

Authors: K Akahane, T Sanda, M R Mansour, T Radimerski, D J DeAngelo, D M Weinstock, A T Look

Institutions: Harvard University, Dana-Farber Cancer Institute, National University of Singapore, Cancer Science Institute of Singapore, University College London, Novartis (Switzerland), Novartis Institutes for BioMedical Research, Boston Children's Hospital

Language: English

Topic: Heat shock proteins research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Center for Chronic Disease Prevention and Health Promotion

Awards: Discovery of New Targets and Pathways for T-ALL Therapy, G2635566763, Molecular Pathways to Thynmic Lymphoma and Leukemia, Development of Novel Therapeutic Strategies in Human Leukemias

OpenAlex ID: W2138725796

FWCI: 2.748

Cites: 41

Cited by: 49

Related to: 10