Work

Tomographic imaging via spectral encoding of spatial frequency

Year: 2013

Type: article

Abstract: Three-dimensional optical tomographic imaging plays an important role in biomedical research and clinical applications. We introduce spectral tomographic imaging (STI) via spectral encoding of spatial frequency principle that not only has the capability for visualizing the three-dimensional object at sub-micron resolution but also providing spatially-resolved quantitative characterization of its structure with nanoscale accuracy for any volume of interest within the object. The theoretical basis and the proof-of-concept numerical simulations are presented to demonstrate the feasibility of spectral tomographic imaging.

Source: Optics Express

DOI: 10.1364/oe.21.007488

Authors: Shikhar Uttam, Sergey A. Alexandrov, Rajan K. Bista, Yang Liu

Institutions: University of Pittsburgh, Ollscoil na Gaillimhe – University of Galway

Language: English

Topic: Digital Holography and Microscopy

Subfield: Atomic and Molecular Physics, and Optics

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $2,270

Funders: National Institutes of Health, National Cancer Institute