Work

Une approche phylo-HMM pour la recherche de séquences

Year: 2008

Type: conference-paper

Abstract: We introduce a new type of phylogenetic Hidden Markov Model, combining the strength of usual HMM and the knowledge of the phylogeny of a family of sequences.We use such models to look into the genome of a target species for members of the sequence family. Our results on some 690 protein families show a better sensitivity and a better specificity when compared to standard profile HMM or Blast searchs.

Source: HAL

Authors: Domelevo Entfellner, Jean-Baka, Gascuel, Olivier

Institutions: École Normale Supérieure Paris-Saclay, Centre National de la Recherche Scientifique, Laboratoire d'Informatique, de Robotique et de Microélectronique de Montpellier

Language: French

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: Agence Nationale de la Recherche

OpenAlex ID: W2139113680

FWCI:

Cites: 11

Cited by:

Related to: 10