Work

Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases

Year: 2001

Type: article

Source: Journal of Molecular Biology

DOI: 10.1006/jmbi.2001.5074

Authors: Peter H Sayre, Janet S Finer-Moore, Timothy A Fritz, Donna Biermann, Susan B Gates, Warren C MacKellar, Vinod F Patel, Robert M Stroud

Institutions: University of California, San Francisco, Eli Lilly (United States)

Language: English

Topic: Biochemical and Molecular Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: CA Technologies, National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: G4666537, G4793966638, SPECIES-SPECIFIC ENZYME INHIBITION BY PHAGE DISPLAY, STRUCTURE BASED DRUG DESIGN

OpenAlex ID: W2139296690

FWCI: 1.303

Cites: 62

Cited by: 59

Related to: 10