New Frontiers in Translational Research in Neuro-oncology and the Blood-Brain Barrier: Report of the Tenth Annual Blood-Brain Barrier Disruption Consortium Meeting
Year: 2005
Type: article
Abstract: The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. For this reason, a meeting partially funded by an NIH R13 grant was convened to discuss recent advances and future directions in translational research in neuro-oncology and the BBB. Cell biology and transport across the BBB, delivery of agents to the CNS, neuroimaging, angiogenesis, immunotherapy, and gene therapy, as well as glioma, primary CNS lymphoma, and metastases to the CNS were discussed. Transport across the BBB relates to the neurovascular unit, which consists not only of endothelial cells but also of pericyte, glia, and neuronal elements.
Source: Clinical Cancer Research
Authors: Nancy D. Doolittle, Lauren E. Abrey, W. Archie Bleyer, Steven Brem, Thomas P. Davis, Paula Dore-Duffy, Lester R. Drewes, Walter A. Hall, John M. Hoffman, Agnieszka Korfel, Robert Martuza, Leslie L. Muldoon, David Peereboom, Darryl R. Peterson, Samuel D. Rabkin, Quentin Smith, Glen H.J. Stevens, Edward A. Neuwelt
Institutions: Oregon Health & Science University, Memorial Sloan Kettering Cancer Center, The University of Texas MD Anderson Cancer Center, University of South Florida, Moffitt Cancer Center, University of Arizona, Wayne State University, University of Minnesota, University of Minnesota, Duluth, National Institutes of Health, National Cancer Institute, Charité – Universitätsmedizin Berlin, Harvard University, Massachusetts General Hospital, Cleveland Clinic, Rosalind Franklin University of Medicine and Science, Texas Tech University
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2139554501