Ocena wpływu czasu podawania heparyny chorym z ostrym zawałem serca przed zabiegiem pierwotnej angioplastyki wieńcowej na przepływ w tętnicy dozawałowej
Year: 2003
Type: article
Study design: Observational Study
Abstract: Assessment of the influence of time of heparin pretreatment for primary angioplasty on the initial flow in the infarct-related artery in patients with acute myocardial infarctionBackground: Normal initial coronary flow (TIMI-3) before mechanical reperfusion is the independent determinant of survival in acute myocardial infarction (AMI).The aim of this study is to assess the influence of heparin administered before the primary PTCA on initial coronary flow in the infarct-related artery.Material and methods: 273 patients with AMI (within 12 h from the onset of symptoms) were included into the study.Study group consisted of 119 patients, who received heparin at the admission to the emergency room of community hospital, before the transfer for primary PTCA to the referral centre.Control group were 154 patients, who received heparin at the CCU of the referral centre.Aspirin was administered for patients of both groups.We compared the initial flow in infarct-related artery and success rate of primary PTCA in both groups.Results: Baseline clinical characteristics were comparable in both groups.The time of transport and time of pre-procedural heparin administration were significantly longer in the study group (p < 0.0001).The initial flow in infarct-related artery was significantly shorter in the study group (p = 0.002), procedural success rate was similar in both groups (97.5% vs. 97.4%).Conclusions: Early administration of heparin and aspirin at the community hospitals in patients transferred for primary PTCA results in better initial flow in infarct-related artery.
Source: Via Medica Journals
Language: Polish
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2139644421