Work

The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode

Year: 2010

Type: article

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2010.06.040

Authors: Maris A. Cinelli, Andrew E. Morrell, Thomas S. Dexheimer, Keli Agama, Surbhi Agrawal, Yves Pommier, Mark Cushman

Institutions: Purdue University West Lafayette, Purdue University Institute for Cancer Research, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Cancer therapeutics and mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute

Awards: G17846721, G4093230697, G6518574306, G675219647

OpenAlex ID: W2139792285

FWCI: 0.948

Cites: 63

Cited by: 23

Related to: 10