Work

Unique neoantigens expressed by melanomas and common epithelial cancers presented by multiple HLA alleles can be efficiently identified utilizing peptide prediction algorithms

Year: 2015

Type: article

Abstract: Meeting abstracts Previous observations indicate that complete regression of metastatic melanoma can be mediated by CD8 lymphocytes that predominantly recognize unique tumor specific mutations predicted in-silico to bind in context of HLA-A*02:01 [[1][1]]. The goal of this project was to expand

Source: Journal for ImmunoTherapy of Cancer

DOI: 10.1186/2051-1426-3-s2-p57

Authors: Kasia Trebska-Mcgowan, Mini Bharathan, Jared J Gartner, Todd D Prickett, Steven A Rosenberg, Paul F Robbins

Institutions: National Institutes of Health, National Cancer Institute

Language: English

Topic: vaccines and immunoinformatics approaches

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490