Work

Clinical and Molecular Epidemiology of Escherichia coli Sequence Type 131 among Hospitalized Patients Colonized Intestinally with Fluoroquinolone-Resistant E. coli

Year: 2014

Type: article

Study design: Observational Study

Abstract: This study examined molecular and epidemiologic factors associated with Escherichia coli sequence type 131 (ST131) among hospitalized patients colonized intestinally with fluoroquinolone (FQ)-resistant E. coli between 2002 and 2004. Among 86 patients, 21 (24%) were colonized with ST131. The proportion of ST131 isolates among colonizing isolates increased significantly over time, from 8% in 2002 to 50% in 2004 (P = 0.003). Furthermore, all 19 clonally related isolates were ST131. Future studies should identify potential transmissibility differences between ST131 and non-ST131 strains.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.03256-14

Authors: Jennifer H. Han, Brian Johnston, Irving Nachamkin, Pam Tolomeo, Warren B. Bilker, Xiangqun Mao, Connie Clabots, Ebbing Lautenbach, James R. Johnson

Institutions: University of Pennsylvania, University of Minnesota, Minneapolis VA Medical Center

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, Office of Research and Development, National Institutes of Health, Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases

Awards: Mentoring and patient-oriented research in antimicrobial resistance, SOUTHEASTERN PENNSYLVANIA ADULT AND PEDIATRIC PREVENTION EPICENTER NETWORK, G3504647095, Carbapenem-Resistant Klebsiella Pneumoniae in Long-Term Acute Care Hospitals, G8017455262

OpenAlex ID: W2139888756

FWCI: 0.915

Cites: 25

Cited by: 8

Related to: 10