Work

The modification of siRNA with 3′ cholesterol to increase nuclease protection and suppression of native mRNA by select siRNA polyplexes

Year: 2010

Type: article

Source: Biomaterials

DOI: 10.1016/j.biomaterials.2010.10.019

Authors: Vishakha V. Ambardekar, Huai-Yun Han, Michelle L. Varney, Serguei V. Vinogradov, Rakesh K. Singh, Joseph A. Vetro

Institutions: University of Nebraska Medical Center, Nebraska Medical Center

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources

Awards: G1544212162, Bioengineering of the blood-brain barrier permeability, Nebraska Center for Nanomedicine, G5175398992, Development of Targeted Nanogels for siRNA Delivery to Tumor Vasculature

OpenAlex ID: W2140337366

FWCI: 1.692

Cites: 33

Cited by: 43

Related to: 10