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Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

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Year: 2012
Type: article
Source: Cell
DOI: 10.1016/j.cell.2012.08.002
Authors: Dongbo Yu, Hannah Pendergraff, Jing Liu, Holly B. Kordasiewicz, Don W. Cleveland, Eric E. Swayze, Walt F. Lima, Stanley T. Crooke, Thazha P. Prakash, David R. Corey
Institutions: The University of Texas Southwestern Medical Center, Ionis Pharmaceuticals (United States), University of California San Diego
Language: English

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: Wellcome Trust, U.S. Public Health Service, National Institute of General Medical Sciences
Awards: Allele-Selective Inhibitors for Expanded Trinucleotide Repeat Genes, RNA processing proteins and neurodegeneration: exploring mechanisms and modelling disease., G8594831391
OpenAlex ID: W2140348270
FWCI: 11.26
Cites: 54
Cited by: 282
Related to: 8
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