Effects of Helicobacter pylori infection and long-term proton pump inhibitor use on enterochromaffin-like cells.
Year: 2012
Type: article
Study design: Observational Study
Abstract: BACKGROUND: infection and long-term proton pump inhibitors (PPI) use on ECL cells. METHODS: -negative and continuously treated with PPI for more than 6 months before the subject recruitment period. The features of ECL cell in oxyntic glands were examined with electron microscopy on biopsy specimens. RESULTS: ECL cells were completely normal in Group A. In group B, moderate hyperplasia and vacuolization was seen in ECL cells. In group C, ECL cell hyperplasia was observed and vacuoles with greater amounts of granules in enlarged vesicles were found more intensely in cytoplasm. CONCLUSION: infection are risk factors for ECL hyperplasia.
Source: PubMed Central
Institution: Ankara University
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2140573152