Work

Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature

Year: 2013

Type: article

Abstract: The effects of salt concentration and temperature on the thermodynamics of DNA minor groove binding have quite different signatures: binding enthalpy is salt concentration independent but temperature dependent. Conversely, binding free energy is salt dependent but essentially temperature independent through enthalpy-entropy compensation.

Source: Chemical Communications

DOI: 10.1039/c3cc44569k