Work

Localisation of oestrogen receptors (ERalpha and ERbeta) in the human and rat epididymides.

Year: 2003

Type: article

Abstract: The aim of the study was to compare the localisation of oestrogen receptors alpha and beta (ER alpha and ER beta) in the human and rat epididymides. In the human epididymis the immunoexpression for ER alpha was detected in the nuclei of the caput epithelial cells, while positive reaction for ER alpha was observed in the nuclei of the cauda epithelial cells. In the rat epididymis, immunoexpression for ER alpha showed nuclei of the caput and cauda epithelial cells. However, the reaction was stronger in cells of the caput epididymis. A positive reaction for ER beta was observed in the nuclei of smooth muscle cells of the epididymal duct and in the nuclei of interstitial tissue cells of the rat caput and cauda epididymis. We have demonstrated that localisation of ER alpha and ER beta is cell-, region- and species-dependent.

Source: PubMed

Authors: Agnieszka Kolasa, Barbara Wiszniewska, Mariola Marchlewicz, Lidia Wenda-Rózewicka

Institution: Pomeranian Medical University

Language: English

Topic: Estrogen and related hormone effects

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2141795795

FWCI: 0.111

Cites: 10

Cited by: 13

Related to: 10