Work

Increased Sporulation Rate of Epidemic Clostridium difficile Type 027/NAP1

Year: 2008

Type: article

Abstract: Clostridium difficile PCR ribotype 027 comprised 0.2% of a collection of Swedish isolates in 1997-2001 (3 of 1,325 isolates). These isolates had lower moxifloxacin MICs than the epidemic type 027 isolates, but they had the same tcdC sequence and toxin yield. Type 027 produced 3- to 13-fold more toxin than did major Swedish types. One epidemic strain (027/NAP1a) sporulated more than did other type 027 isolates, a feature that should contribute to its survival and spread.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.01964-07

Authors: Thomas Åkerlund, Ingela Persson, Magnus Unemo, Torbjörn Norén, Bo Svenungsson, Marlene Wullt, Lars G. Burman

Institutions: Swedish Institute, Örebro University Hospital, Karolinska University Hospital, Lund University

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2141951202

FWCI: 15.11

Cites: 37

Cited by: 236

Related to: 10