Work

Magnetic Tagging of Therapeutic Cells for MRI

Year: 2009

Type: review

Abstract: Transplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically labeled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.

Source: Journal of Nuclear Medicine

DOI: 10.2967/jnumed.108.053546

Authors: Matthew D. Budde, Joseph A. Frank

Institutions: National Institutes of Health, National Institutes of Health Clinical Center

Language: English

Topic: Mesenchymal stem cell research

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, NIH Clinical Center