Work

End Point Assessment in Gliomas: Novel Treatments Limit Usefulness of Classical Macdonald's Criteria

Year: 2009

Type: article

Abstract: Recent trials in glioma have revealed significant limitations in the end points used. This requires a critical and comprehensive review of how brain tumor trials are conducted, particularly of which end points are defined and how response and progression are defined.

Source: Journal of Clinical Oncology

DOI: 10.1200/jco.2009.22.4998

Authors: Martin J. van den Bent, Michael A. Vogelbaum, Patrick Y. Wen, David R. Macdonald, Susan M. Chang

Institutions: Erasmus MC, Daniel den Hoed Kliniek, Cleveland Clinic, Brigham and Women's Hospital, Center for Neuro-Oncology, Dana-Farber Brigham Cancer Center, Western University, University of California, San Francisco

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Bristol-Myers Squibb, American Society of Clinical Oncology, Merck KGaA, National Institutes of Health, Genentech, National Cancer Institute

Award: Imaging and Genomic Signatures of Brain Tumor Heterogeneity and Evolution to Optimize Patient Management

OpenAlex ID: W2142312148

FWCI: 16.69

Cites: 39

Cited by: 240

Related to: 10