Work

A mechanical basis for chromosome function

Year: 2004

Type: article

Abstract: We propose that chromosome function is governed by internal mechanical forces generated by programmed tendencies for expansion of the DNA/chromatin fiber against constraining features.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.0402724101

Authors: Nancy Kleckner, Denise Zickler, Gareth H. Jones, Job Dekker, Ruth Padmore, Jim Henle, John Hutchinson

Institutions: Université Paris-Sud, Harvard University, University of Massachusetts Chan Medical School, University of Birmingham

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Human Genome Research Institute, National Institute of General Medical Sciences

Awards: ILLEGITIMATE RECOMBINATION BY DRUG RESISTANCE ELEMENTS, G4669245020, Illegitimate Recombination by Drug Resistance Elements, Meiotic Chromosome Synapsis and Recombination in Yeast, Structural Annotation of the Human Genome

OpenAlex ID: W2142860698

FWCI: 4.715

Cites: 38

Cited by: 339

Related to: 8