Work

Capgras-like visual decomposition in Lewy body dementia with therapeutic response to donepezil

Year: 2014

Type: article

Abstract: Defects in visual/spatial cognition, including hallucinations and Capgras syndrome, are common in Lewy body dementia (LBD).1 In Capgras syndrome, a person holds a delusion that a friend, spouse, parent, or other close family member has been replaced by an identical-looking impostor. These visual phenomena frequently induce anxiety and agitation, and the only treatment currently available is neuroleptics. Neuroleptics have severe side effects in LBD as well as a black box warning for increased risk of death and stroke in elderly patients with dementia. We report 2 cases of LBD where visual phenomena including Capgras-like syndrome responded favorably to the use of a cholinesterase inhibitor.

Source: Neurology Clinical Practice

DOI: 10.1212/cpj.0000000000000068

Authors: Karen Reimers, Natalie Emmert, Harshit Shah, Ralph H.B. Benedict, Kinga Szigeti

Institution: University at Buffalo, State University of New York

Language: English

Topic: Parkinson's Disease Mechanisms and Treatments

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2142994904

FWCI: 0.217

Cites: 7

Cited by: 5

Related to: 10