Work

Fluorine‐Enabled Cationic Gold Catalysis: Functionalized Hydration of Alkynes

Year: 2010

Type: article

Abstract: Fluorine makes it possible: A cationic fluorine–gold species generated by fluorination of a low-valence gold complex mediates the “functionalized hydration” of alkynes. A triple bond is used to install a carbonyl group and two new bonds on the α-carbon atom, all occurring in one pot, under mild conditions and in very good yields (see scheme).

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201003593

Authors: Weibo Wang, Jacek Jasinski, Gerald B. Hammond, Bo Xu

Institution: University of Louisville

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: National Science Foundation, University of Louisville, Division of Chemistry, Office of Experimental Program to Stimulate Competitive Research

Awards: Building Kentucky's New Economy with EPSCoR, Alkynylogation and transformative fluorination in synthesis