Work

Development of synthetic membrane transporters for anions

Year: 2006

Type: review

Abstract: The development of low molecular weight anion transporters is an emerging topic in supramolecular chemistry. The major focus of this tutorial review is on synthetic chloride transport systems that operate in vesicle and cell membranes. The transporters alter transmembrane concentration gradients, and thus they have applications as reagents for cell biology research and as potential chemotherapeutic agents. The molecular designs include monomolecular channels, self-assembled channels and mobile carriers. Also discussed are the experimental assays that measure transport rates across model bilayer membranes.

Source: Chemical Society Reviews

DOI: 10.1039/b512651g

Authors: Anthony P. Davis, David N. Sheppard, Bradley D. Smith

Institutions: University of Bristol, University of Notre Dame

Language: English

Topic: Supramolecular Chemistry and Complexes

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Molecular Probes for Biomembrane Recognition