Work

Dinuclear {(salen)Al} Complexes Display Expanded Scope in the Conjugate Cyanation of α,β‐Unsaturated Imides

Year: 2008

Type: article

Abstract: Al together: Covalently linked dinuclear {(salen)Al} complexes catalyze the conjugate cyanation of α,β-unsaturated imides with several orders of magnitude greater reactivity over the mononuclear analogue, and with comparable enantioselectivity. Imides that were completely unreactive with homo- and heterobimetallic combinations of mononuclear catalysts can now be converted into the corresponding cyanation products with high enantiomeric excess.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200704461

Authors: Clément Mazet, Eric N. Jacobsen

Institution: Harvard University

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: G2091016619