Association of occult chronic kidney disease with cardiovascular risk and their risk factors in university workers
Year: 2011
Type: article
Study design: Observational Study
Abstract: Occult chronic kidney disease (OCKD) and cardiovascular risk (CVR) share risk factors that trigger chronic degenerative diseases. Aim. To assess the association of OCKD with CVR and its risk factors in a sample of university workers. Material and methods. This is a crosssectional study. From 89 volunteers the lipid profile, glucose, urea, creatinine and uric acid were obtained from blood as well as anthropometric measures and blood pressure. They were classified by their CVR calculated by the Framingham equation, into the groups: with-CVR and without-CVR; and by their glomerular filtration rate (GFR) into: with-OCKD and without-OCKD. Then into subgroups of each CVR factor (CVRF): sex, smoking, diabetes mellitus (DM) and hypertension. The statistical differences between groups (p 0.05) and the correlation between CVR and GFR and the odds ratio (OR) for each CVRF were determined. Results. A negative correlation between the OCKD and the CVR was obtained for men (p = - 0.743, p = 0.000) and women (p = - 0.874, p = 0.000). The overall prevalence of hypertension was 23.6% (OR = 15.43 for CVR, 95% CI, 4.04 - 58.95, OR = 14.75 for OCKD, 95% CI 2.76 - 78.23) and older than 50 years of 33.7% (OR for CVR = 20.37, 95% CI, 6.25 - 66.43). Conclusions. OCKD is strongly associated with the CVR. Furthermore, each CVRF impacts in different range and level to the development of cardiovascular disease and kidney failure.
Source: Americanae (AECID Library)
Authors: Angélica Jimenez-Rosales, Victoria Domínguez, Gilberto F. Vázquez-De Anda, Gerardo Huitrón Bravo
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2144247903