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Discovery and Characterization of a G Protein–Biased Agonist That Inhibits β-Arrestin Recruitment to the D2 Dopamine Receptor

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Year: 2014
Type: article
Source: Molecular Pharmacology
DOI: 10.1124/mol.113.090563
Authors: R. Benjamin Free, Lani S. Chun, Amy E. Moritz, Brittney N. Miller, Trevor B. Doyle, Jennie L. Conroy, Adrian Padron, Julie A. Meade, Jingbo Xiao, Xin Hu, Andrés E. Dulcey, Yang Han, Lihua Duan, Steve Titus, Melanie Bryant-Genevier, Elena Barnaeva, Marc Ferrer, Jonathan A. Javitch, Thijs Beuming, Lei Shi, Noel T. Southall, Juan J. Marugan, David R. Sibley
Institutions: National Institutes of Health, Johns Hopkins University, Schrodinger (United States), Cornell University, National Institute of Neurological Disorders and Stroke, National Center for Advancing Translational Sciences, Weill Cornell Medicine, New York State Psychiatric Institute, Columbia University
Language: English

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of Mental Health, National Institute on Drug Abuse
Awards: Molecular determinants for the action of psychostimulants, Structure and Function of Dopamine Receptors, G94731328
OpenAlex ID: W2145094745
FWCI: 3.407
Cites: 44
Cited by: 84
Related to: 10
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