Work

PopHist: inferring population history from the spectrum of allele frequencies

Year: 2003

Type: article

Abstract: SUMMARY: PopHist is a computer program that uses the frequency spectrum of alleles to: (a) estimate maximum likelihood parameters describing a population's history; and (b) compare alternative hypotheses about population history using likelihood ratio tests. The program uses the matrix coalescent, a method for calculating theoretical frequency spectra that can be applied to sets of unlinked sites. AVAILABILITY: Source code and documentation are available at http://mombasa.anthro.utah.edu/wooding/PopHist

Source: Bioinformatics

DOI: 10.1093/bioinformatics/btg024

Author: Stephen Wooding

Institution: University of Utah

Language: English

Topic: Genetic diversity and population structure

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: University of Utah, National Institutes of Health

OpenAlex ID: W2145356757