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Comparison of thyroid volume and goiter measured by means of ultrasonography and SPECT with use of 131I and 99m)c in smokers and non-smokers.

Year: 2009
Type: article
Study design: Observational Study
Abstract: INTRODUCTION: The aim of the study was to estimate the influence of nicotine on thyroid volume according to patients' sex. MATERIAL AND METHODS: A group of 160 patients with thyroid disorders in their past medical history was examined. Patients were divided into two groups: Group A contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and (131)I-SPECT; group B contained 50 patients with goiter, where the volume of the thyroid was evaluated with use of US and (99m)Tc-SPECT. There were two control groups: Group A' contained 30 patients with normal volume of the thyroid gland shown by US and (131)I-SPECT, and group B' contained 30 patients with normal volume of the thyroid gland shown by US and (99m)Tc-SPECT. The patients from the examined and control groups were divided into two subgroups - smokers and non-smokers. US of the thyroid gland was made by means of an ALOKA SSD 500 device. SPECT was performed by means of a singke-headed gamma camera by Diacam. RESULTS: The average volume of thyroid gland measured by (131)I-SPECT and (99m)Tc-SPECT was significantly larger according to US in the examined and control groups in smokers and non-smokers. We did not show statistically significant correlations between levels of iodine uptake and volumes of goiter evaluated by US examination together with (131)I scintigraphy. CONCLUSIONS: Significant differences in average values of thyroid volume between smokers and non-smokers were not observed, which might suggest a lack of goitrogenic activity of tobacco smoke or indicates a potential goitrogenic influence not significant enough in the examined group.
Source: PubMed
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W2145567145
FWCI:
Cites: 21
Cited by: 1
Related to: 10