Work

Next-generation personalized drug discovery: the tripeptide GHK hits center stage in chronic obstructive pulmonary disease

Year: 2012

Type: article

Abstract: Chronic lung diseases (CLDs), including chronic obstructive pulmonary disease (COPD), are the second leading cause of death worldwide. The first report of database-driven drug discovery in carefully phenotyped COPD specimens has now been published in Genome Medicine, combining gene expression data in defined emphysematous areas with connectivity-map-based compound discovery. This joint effort may lead the way to novel and potentially more efficient concepts of personalized drug discovery for COPD in particular, and CLD in general. See research article http://genomemedicine.com/content/4/8/67/abstract.

Source: Genome Medicine

DOI: 10.1186/gm371

Authors: Silke Meiners, Oliver Eickelberg

Institutions: Helmholtz Munich, German Center for Lung Research, Ludwig-Maximilians-Universität München

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,290