Work

Coordinated Activation of Caspases and Apoptosis in Allogeneic Antigen Stimulated Human T Cells

Year: 2001

Type: article

Abstract: Activation of caspases is generally associated with induction of apoptosis in many cell types (1).Stimulation of normal human T lymphocytes with allogeneic antigens or mitogen leads to cell proliferation as well as caspase-3 activation, suggesting that caspases may also have functions other than apoptosis (2-3).However, the role of caspases in human T cell apoptosis remains unclear.The aim of our study was to define the role of caspases in human T cell apoptosis.

Source: The Scientific World JOURNAL

DOI: 10.1100/tsw.2001.163

Authors: Sundararajan Jayaraman, John N. Barrett

Institution: University of Miami

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $860