Work

Rationale for Reading Fluconazole MICs at 24 Hours Rather than 48 Hours When Testing Candida spp. by the CLSI M27-A2 Standard Method

Year: 2008

Type: article

Abstract: We investigated if CLSI M27-A2 Candida species breakpoints for fluconazole MIC are valid when read at 24 h. Analysis of a data set showed good correlation between 48- and 24-h MICs, as well as similar outcomes and pharmacodynamic efficacy parameters, except for isolates in the susceptible dose-dependent category, such as Candida glabrata.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00420-08

Authors: Luis Ostrosky-Zeichner, John H. Rex, Michael A. Pfaller, Daniel J. Diekema, Barbara D. Alexander, David Andes, Steven D. Brown, Vishnu Chaturvedi, Mahmoud A. Ghannoum, Cindy C. Knapp, Daniel J. Sheehan, Thomas J. Walsh

Institutions: The University of Texas Health Science Center at Houston, AstraZeneca (United Kingdom), University of Iowa, Duke University, University of Wisconsin–Madison, New York State Department of Health, Case Western Reserve University, Pfizer (United States), National Institutes of Health, National Cancer Institute

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2145813802

FWCI: 4.723

Cites: 17

Cited by: 45

Related to: 10