The role of probiotics in pouchitis Georgios Nalmpantidis, Theofanis Maris.
Year: 2012
Type: article
Abstract: In their invited narrative review article, Gionchetti et al (April-June issue) [1] report 6 studies in which probiotics were used for maintenance of remission in pouchitis or induction of remission in acute pouchitis. In all but one studies VSL#3 probiotic was used. In 4 studies treatment group (VSL#3 regi-men was used in 3 studies) was compared to a control group [2-5]. [Q1. references are missing]. The studies of VSL#3 may form a coherent group, although the duration of treatment varied between 9 and 12 months. A recent meta-analysis of probiotic efficacy for gastrointestinal diseases synthesized data of 4 studies of pouchitis treatment [6]. In this systematic review the relative risk ratio for the probiotic group was 0.17 [95 % Confidence Interval (CI) 0.10-0.30]. However, most of the studies cited by the article of Gionchetti et al were not included in this meta-analysis. The heterogeneity among the
Source: Europe PMC (PubMed Central)
Authors: Georgios Nalmpantidis, Thessaloniki Maris
Language: English
Topic: Inflammatory Bowel Disease
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2146067810