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Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival

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Year: 2005
Type: article
Source: Molecular Cancer Therapeutics
DOI: 10.1158/1535-7163.257.4.2
Authors: Rubén W. Carón, Adly Yacoub, Min Li, Xiaoyu Zhu, Clint Mitchell, Young Hong, William Hawkins, Takehiko Sasazuki, Senji Shirasawa, Alan P. Kozikowski, Philip A. Dennis, Michael P. Hagan, Steven Grant, Paul Dent
Institutions: Consejo Nacional de Investigaciones Científicas y Técnicas, Instituto de Medicina y Biología Experimental de Cuyo, University of Illinois Chicago, National Cancer Institute, Virginia Commonwealth University
Language: English

Topic: Protein Kinase Regulation and GTPase Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: G240198448, G2447325627, G2809070691, Carcinoma cell radiosensitization by MAPK inhibition, Signaling Pathways Regulating Epithelial Cell Survival, Genetic Modulation of Cellular Radiation Responses, Promotion of Nucleoside Analog Induced Apoptosis by HDIs, G675329814, G680599012
OpenAlex ID: W2146149227
FWCI: 3.915
Cites: 45
Cited by: 85
Related to: 10
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