Work

[2+2] Cycloaddition of 1,3‐Dienes by Visible Light Photocatalysis

Year: 2014

Type: article

Abstract: [2+2] photocycloadditions of 1,3-dienes represent a powerful yet synthetically underutilized class of reactions. We report that visible light absorbing transition metal complexes enable the [2+2] cycloaddition of a diverse range of 1,3-dienes. The ability to use long-wavelength visible light is attractive because these reaction conditions tolerate the presence of sensitive functional groups that might be readily decomposed by the high-energy UVC radiation required for direct photoexcitation of 1,3-dienes. The resulting vinylcyclobutane products are poised for a variety of further diversification reactions, and this method is consequently expected to be powerfully enabling in the synthesis of complex organic targets.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201405359

Authors: Anna E. Hurtley, Zhan Lu, Tehshik P. Yoon

Institution: University of Wisconsin–Madison

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Visible Light Photocatalysis